Features

Diagnosis where? Testing Pigs and Humans for T. solium cysticercosis in Uganda

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Taenia solium is a zoonotic disease shared between humans and pigs. Humans become infected with T. solium, also known as the pork tapeworm, when they consume undercooked pork infected with porcine cysticercosis. Human cysticercosis develops when humans ingest T. solium eggs. If cysterici travel to the human brain this leads to neurocysticercosis, a leading cause of onset epilepsy in endemic …

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Humanitarian diagnostics for sleeping sickness in Uganda

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A key impetus for the invention of a Rapid Diagnostic Test (RDT) for sleeping sickness (also known as human African trypanosomiasis or HAT) was the persuasive advocacy for better ‘field ready tools’ by medical humanitarian agencies such as Médecins Sans Frontières. They were engaged in fighting outbreaks of this disease, which is fatal if untreated, in contexts of weakened health …

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Diagnostics without diagnosis: RDTs for Sleeping Sickness in Uganda

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Diagnosing sleeping sickness (also known as human African trypanosomiasis (HAT)) is complicated, requiring the alignment of clinical suspicion with serological, parasitological, and molecular confirmation to determine appropriate treatment. Previously, diagnosis was carried out by mobile lab teams which confirmed cases in village screenings and transported patients for treatment. Since cases have declined however, expensive active screening campaigns have been phased …

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Laboratory capacity building and the open hardware movement

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Through my work in African laboratories I am regularly made aware of the challenging equipment shortages faced by research laboratories in many low/middle-income countries (LMICs). This extends far beyond the absence of “state-of-the-art” equipment and shiny, new models regularly produced by commercial companies. These shortages include the availability of what would normally be considered ubiquitous laboratory equipment – PCR machines, …

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ReEBOV: Developing an Ebola rapid diagnostic test at research ground zero

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In June 2015, as Sierra Leone and Guinea was experiencing new surges in clusters of Ebola virus cases, Nature published a news article asking why an inexpensive test that “could save lives” was not being deployed to the field. Indeed, while it seemed obvious to many policy makers and health experts that Ebola rapid diagnostic tests were urgently needed, the …

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Conjuring Madness: Self/Non Self and Mental Illness in Post-Apartheid Namibia

Il convient plutot de s’attacher à ce que signifie ȇtre un homme, avant de problématiser la folie en terms de santé et maladie, Ludwig Binswanger, Le Rȇve et l’Existence (1954)

 

On a cold winter morning I walked on Independence Avenue, Windhoek’s main thoroughfare in the heart of the capital’s central business district, with M. …